A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s
نویسندگان
چکیده
منابع مشابه
A common conformationally coupled ATPase mechanism for yeast and human cytoplasmic HSP90s
The conformationally coupled mechanism by which ATP is utilized by yeast Hsp90 is now well characterized. In contrast, ATP utilization by human Hsp90s is less well studied, and appears to operate differently. To resolve these conflicting models, we have conducted a side-by-side biochemical analysis in a series of mutant yeast and human Hsp90s that have been both mechanistically and structurally...
متن کاملpassivity in waiting for godot and endgame: a psychoanalytic reading
this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...
Activation of G-protein-coupled receptors: a common molecular mechanism.
G-protein-coupled receptors (GPCRs) are a large family of proteins that contain a seven transmembrane helical structural motif. They mediate responses to several ligands by binding and activating intracellular heterotrimeric G proteins. Since the cloning of the first GPCR, insights gained from structure-function studies, genetics and drug development have contributed to uncovering a common mech...
متن کاملCoupled Coincidence and Common Fixed Point Theorems for Single-Valued and Fuzzy Mappings
In this paper, we study the existence of coupled coincidence andcoupled common fixed points for single-valued and fuzzy mappingsunder a contractive condition in metric space. Presented theoremsextend and improve the main results of Abbas and$acute{C}$iri$acute{c}$ {itshape et al.} [M. Abbas, L.$acute{C}$iri$acute{c}$, {itshape et al.}, Coupled coincidenceand common fixed point theorems for hybr...
متن کاملCoupled coincidence point and common coupled fixed point theorems in complex valued metric spaces
In this paper, we introduce the concept of a w-compatible mappings and utilize the same to discuss the ideas of coupled coincidence point and coupled point of coincidence for nonlinear contractive mappings in the context of complex valued metric spaces besides proving existence theorems which are following by corresponding unique coupled common fixed point theorems for such mappings. Some illus...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: FEBS Journal
سال: 2008
ISSN: 1742-464X
DOI: 10.1111/j.1742-4658.2008.06773.x